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In some patients, MGUS may later become a more serious condition or cancer, such as multiple myeloma or lymphoma.In rare cases, multiple myeloma can cause organs to fail.Sometimes multiple myeloma does not cause any symptoms.The following symptoms may be caused by multiple myeloma or other conditions.

In most patients, the amount of M protein stays the same and there are no symptoms or problems.The thickened blood may cause problems with blood flow in small blood vessels.Symptoms of macroglobulinemia depend on the part of the body affected.This condition may cause anemia or easy bleeding, or make it easier to get an infection.The abnormal plasma cells often form tumors in bones or soft tissues of the body.

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